IN THE SPOTLIGHT

Discovery reveals role of EGFR in resistance to KRAS inhibitors in pancreatic cancer

Discovery reveals role of EGFR in resistance to KRAS inhibitors in pancreatic cancer

‘I am 52, not diabetic, BP 130/90 but my creatinine is 1.35 and eGFR 55. What do I do to stop further deterioration? My weight is 90 kg’

‘I am 52, not diabetic, BP 130/90 but my creatinine is 1.35 and eGFR 55. What do I do to stop further deterioration? My weight is 90 kg’

Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and experimental evaluation

Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and experimental evaluation

Multiplex gene-editing strategy to engineer allogeneic EGFR-targeting CAR T-cells with improved efficacy against solid tumors

Multiplex gene-editing strategy to engineer allogeneic EGFR-targeting CAR T-cells with improved efficacy against solid tumors

Fructose intake driven glycolysis-ROS-EGFR axis specifically promotes the generation and pathogenicity of Th17 cells

Fructose intake driven glycolysis-ROS-EGFR axis specifically promotes the generation and pathogenicity of Th17 cells

Novel Resistance Mechanisms to Second‐Generation EGFR Tyrosine Kinase Inhibitor Afatinib and Associations With Genomic Features in NSCLC

Novel Resistance Mechanisms to Second‐Generation EGFR Tyrosine Kinase Inhibitor Afatinib and Associations With Genomic Features in NSCLC

Design, Synthesis, Biological Evaluation, and In Silico Studies of Novel Furo[2,3-d]pyrimidine Derivatives as EGFR Inhibitors With Potential Antitumor Activity

Design, Synthesis, Biological Evaluation, and In Silico Studies of Novel Furo[2,3-d]pyrimidine Derivatives as EGFR Inhibitors With Potential Antitumor Activity

Plasma-Based Next-Generation Sequencing Identifies EGFR and ALK Mutations in Asian Patients with Advanced NSCLC

Plasma-Based Next-Generation Sequencing Identifies EGFR and ALK Mutations in Asian Patients with Advanced NSCLC

Design, synthesis, biological evaluation and in-silico study of thioether-linked 4-hydroxycoumarin-benzothiazole derivatives targeting EGFR for cancer therapy

Design, synthesis, biological evaluation and in-silico study of thioether-linked 4-hydroxycoumarin-benzothiazole derivatives targeting EGFR for cancer therapy

CGEM Advances NDA for Zipalertinib Targeting EGFR Mutations in NSCLC

CGEM Advances NDA for Zipalertinib Targeting EGFR Mutations in NSCLC